High-Purity HA-966 HCl for Advanced Neurochemical Research
In the precision-focused fields of neuropharmacology and excitatory amino acid research, HA-966 HCl (chemically identified as 3-amino-1-hydroxy-pyrrolidin-2-one hydrochloride) represents a unique and essential tool. Known for its role as a selective antagonist at the strychnine-insensitive glycine modulatory site of the NMDA receptor complex, HA-966 is a critical reagent for laboratories investigating glutamatergic signaling and synaptic plasticity. Our laboratory-grade HA-966 HCl is synthesized at a minimum purity of 99%, providing the 2026 scientific community with a stable crystalline powder optimized for rigorous analytical and in vitro applications.
Advanced Pharmacological Profile and Analytical Utility
HA-966 is distinguished by its stereospecific activity; while the (R)-(+)-enantiomer acts as a selective glycine/NMDA receptor antagonist, the (S)-(-)-enantiomer is researched for its potent sedative and muscle relaxant properties. Our high-purity racemic hydrochloride salt allows researchers to study:
- Glycine Modulatory Site Interactions: Investigating the competitive inhibition of glycine-potentiated NMDA responses.
- Neuroprotective Modeling: Analyzing the compound’s researched ability to prevent neurotoxicity and its anticonvulsant properties in in vivo models.
- Dopaminergic System Regulation: Exploring how HA-966 interacts with mesocorticolimbic dopamine metabolism, making it a subject of interest for stress and sensitization research.
Our synthesis process ensures a clean analytical profile, free from synthesis precursors and residual solvents, essential for high-precision methods such as HPLC, GC-MS, and NMR spectroscopy.
Key Specifications for Laboratory Research
- Verified Chemical Purity: Minimum 99% purity confirmed via HPLC and NMR testing for consistent and reproducible experimental results.
- Superior Salt Stability: The HCl salt form (CAS 42585-88-6) ensures excellent water solubility and long-term storage viability.
- Standardized Crystalline Form: A fine white powder with a molecular weight of 152.58 g/mol.
- Secure Global Logistics: Optimized shipping protocols for the discreet and rapid delivery of reagents to laboratories across the USA and EU.
Why Partner with Our 2026 Research Supply Catalog?
Sourcing sophisticated NMDA antagonists like HA-966 HCl requires a supplier that understands the transactional intensity and logistical precision of the modern scientific market. We prioritize the security of our materials, utilizing airtight, light-resistant packaging to prevent environmental degradation during transit. As a leader in the e-commerce sector for laboratory reagents, we provide a streamlined procurement process designed to keep your research moving forward. Our 2026 supply chain is optimized for the rapid delivery of high-caliber reagents to verified facilities, ensuring your project timelines remain uninterrupted.
Secure Your Scientific Inventory Today
Due to the specialized synthesis and multi-enantiomer complexity of HA-966, stock availability for the hydrochloride salt is subject to specific production cycles. To ensure your laboratory’s data remains consistent and your research project stays on track, we recommend securing your necessary quantities immediately. Join the global network of specialists who trust our premium reagents for their high-stakes neurochemical modeling.
Add HA-966 HCl to your laboratory inventory today and achieve unparalleled precision in your glutamatergic research!

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